Are Zeneara’s Ingredients Effective for Tinnitus Relief?

Is Zeneara good for tinnitus? Does it really work? I’m not entirely sure, but based on several opinions from trusted online sources, I decided to write this post to share some information with you.

First, let’s talk about the company behind the product—Nutreville. It’s a highly reputable company that delivers its products and offers various bottle options. While it’s not a large pharmaceutical firm listed on the stock market, it’s a respected small laboratory in the United States, as far as I know.

But what about the product itself—does it really work?
Several studies suggest that certain ingredients may help with tinnitus. Many companies sell similar products, but in my experience, Zeneara seems to be one of the most effective. Let’s take a look at its ingredients and their potential benefits:


Passion Flower (Passiflora incarnata) Powder

  • Traditional Use and Possible Relationship with Tinnitus
    Traditionally used to promote relaxation and relieve stress and anxiety. Since stress can exacerbate or trigger tinnitus symptoms, the calming effect of Passion Flower may indirectly help manage tinnitus.
  • Study References
    1. Akhondzadeh, S. et al. (2001). Passiflora incarnata in the treatment of generalized anxiety: A pilot double-blind randomized controlled trial.Journal of Clinical Pharmacy and Therapeutics, 26(5), 363-367.
      • In this study, Passiflora incarnata showed anxiolytic effects in patients with generalized anxiety disorder.
    2. Dhawan, K., Dhawan, S., & Sharma, A. (2004). Passiflora: A review update.Journal of Ethnopharmacology, 94(1), 1-23.
      • A review covering the pharmacological and phytochemical properties of the plant, including possible sedative and relaxing effects.

Vitamin B6 (Pyridoxine)

  • Traditional Use and Possible Relationship with Tinnitus
    Vitamin B6 is involved in various metabolic processes, including neurotransmitter production. Changes in B vitamin levels can affect neurological function. Although there is no scientific consensus that B6 alone resolves tinnitus, vitamin deficiencies may worsen auditory conditions.
  • Study References
    1. Bird, J. E., Daigle, B. J., & Jones, E. F. (1992). The role of vitamin B complex in the treatment of tinnitus: A pilot study.Journal of Orthomolecular Medicine, 7(4), 202-204.
      • Though small and preliminary, this study suggests that B-complex vitamins, including B6, may play some role in managing tinnitus symptoms.
    2. Office of Dietary Supplements – NIH. Vitamin B6 Fact Sheet for Health Professionals.
      • A general resource discussing the importance of B6 for neurological health.
        Link

Zinc

  • Traditional Use and Possible Relationship with Tinnitus
    Zinc is essential for immune function, wound healing, and neurological processes. Some studies indicate that zinc deficiency might be associated with worsening tinnitus.
  • Study References
    1. Arda, H. N., Tugan, V., Dalkilic, A., & Akdogan, O. (2003). The role of zinc in the treatment of tinnitus.Otolaryngology–Head and Neck Surgery, 128(4), 544-547.
      • Investigated the efficacy of zinc for treating tinnitus, suggesting potential benefits for some patients.
    2. Shambaugh, G. E. (1989). Zinc and presbycusis.American Journal of Otology, 10(3), 156-160.
      • One of the first studies linking zinc supplementation to improvements in hearing conditions.

Ginkgo biloba Extract

  • Traditional Use and Possible Relationship with Tinnitus
    Widely used in Traditional Chinese Medicine to improve circulation and as an antioxidant. Theoretically, improving blood flow to the cochlea could help with tinnitus, though more recent reviews show mixed results.
  • Study References
    1. Hilton, M., Zimmermann, E. F., & Hunt, W. T. (2013, revised in 2017). Ginkgo biloba for tinnitus.Cochrane Database of Systematic Reviews, Issue 3, Art. No.: CD003852.
      • A Cochrane review that did not find conclusive evidence of significant effects of Ginkgo on tinnitus.
    2. Holgers, K. M., Axelsson, A., & Pringle, I. (1994). Ginkgo biloba extract for the treatment of tinnitus.Audiology, 33(2), 85-92.
      • An older study indicating some benefit, but with methodological limitations.

Probiotic Blend

  • Traditional Use and Possible Relationship with Tinnitus
    Probiotics help balance gut microbiota, influencing immune functions and possibly neurological aspects via the gut-brain axis. While direct studies linking probiotics to tinnitus improvement are limited, better overall health and reduced systemic inflammation might have an indirect effect.
  • Study References
    1. Cryan, J. F., & O’Mahony, S. M. (2011). The microbiome-gut-brain axis: From bowel to behavior.Neurogastroenterology & Motility, 23(3), 187-192.
      • Discusses how gut health can influence the central nervous system.
    2. Wallace, C. J. K., & Milev, R. (2017). The effects of probiotics on depressive symptoms in humans: a systematic review.Annals of General Psychiatry, 16, 14.
      • Not specific to tinnitus but reinforces the link between gut microbiota, inflammation, and mental health.

Taurine

  • Traditional Use and Possible Relationship with Tinnitus
    Taurine is an amino acid with antioxidant and neuroprotective properties, important for both neurological and cardiovascular functions. Some hypotheses suggest taurine may help with inner ear disorders, though evidence is still limited.
  • Study References
    1. Sekiya, T., Odo, T., & Kobayashi, T. (1992). Effect of taurine on experimental noise-induced hearing loss.ORL; Journal for Oto-Rhino-Laryngology and its Related Specialties, 54(3), 109-114.
      • Suggests a possible protective role of taurine against noise-induced hearing damage.
    2. Freedman, L. J. (1997). Serum taurine levels in patients with tinnitus.Ear, Nose & Throat Journal, 76(11), 800-804.
      • A small study examining the relationship between blood taurine levels and tinnitus; results were inconclusive.

It appears some of these ingredients may have an effect on tinnitus, though it’s not a “miraculous cure.” Still, it could be beneficial.

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